The following is an overview of Dr Zamboni’s research towards his cure for MS. There are additionally links to his published papers for more detailed information.
The big idea:
Iron dependent inflammation in venous disease an proposed parallels in MS
Published in 2006 this is Zamboni’s outline of his theory on how he believed that venous insufficiency could be the cause of MS. This was the first step towards the discovery of CCSVI.
- Link to: The Big Idea(Link Broken)
Doppler haemodynamics test in MS patients
These following two research papers outlines the first and second tests of ECD-TCCS. They include the findings that in all studied cases of MS patients there were at least 2 abnormal veins. The initial test was performed simply to determine if this would prove to be a feasible way of detecting the abnormalities.
The second was an performed as an actual study to on CCSVI to determine if there were a correlation to MS patients. This paper outlines how the first doppler studies of MS patients were performed. Within it describes how in all cases MS patients were found to have at least 2 venous abnormalities.
- Intracranial venous haemodynamics in MS
- The value of cerebral doppler haemodynamics in the assessment of ms
ECD-TCCS Test Procedure
From Dr Zamboni’s findings in his initial test he and his research group compiled what they learned by performing their tests into a document.
If you are trying to get yourself tested, you will likely need this document.
Chronic cerebrospinal venous insufficiency in patients with multiple sclerosis
In this research Dr Zamboni worked with 7 other researchers. With them they perform the doppler test (ECD-TCCS) on all patients and verified the results with a venogram. In all cases the more accurate venogram verified the results of the doppler with the occurrence of the abnormal veins. This results also shows a that there are 4 distinct patterns, concluding that there is a very strong co-relation between people with MS and the occurance of venous abnormalities.
The Liberation Procedure
The prelimary results for the Liberation Procedure study were published for the attendees of a the Charing Cross presentation.
As the study was and is still on going it cannot be consider 100% conclusive. However, initial results showed a considerable decrease in relapses after surgery was performed to enhance the veins. Additionally, it was found from surveys that many patients found they had a reduction in the amount of fatigue they experienced.
It should be noted that this report focuses more on the effect of the treatment on remitting and relapsing patients with the expectation that progressive patients will be included in the final report at the conclusion of the study.
Venous Collateral Circulation of the Extracranial Cerebrospinal Outflow Routes
A detailed explanation about how due to the CCSVI that MS patients are in there is a limited flow of blood from the brain to the heart. This blockage then prevents the proper drainage of flow from certain areas of the brain which is believed to cause the eventual occurrence of MS in patients.
